Is (1-3)-β-D-glucan iyo Isipo Link kubva kuBedside Assessment kuenda kuPre-emptive Therapy yeInvasive.

Invasive candidiasis inogara ichityisidzira hupenyu kune varwere vanorwara zvakanyanya.Kuongororwa kwekutanga kunoteverwa nekurapwa nekukurumidza kwakanangana nekuvandudza mhedzisiro nekudzikisa kusingakoshike kushandiswa kweantifungal kunoramba kuri dambudziko guru muICU.Kusarudzwa kwemurwere panguva yakakodzera saka kunoita basa rakakosha kune kiriniki inoshanda uye inodhura-inoshanda manejimendi.Nzira dzinobatanidza kiriniki yengozi zvinhu uye Candida colonization data yakavandudza kugona kwedu kuziva varwere vakadaro nekukurumidza.Nepo iyo yakaipa yekufungidzira kukosha kwezvibodzwa uye kufanotaura mitemo inosvika 95 kusvika 99%, iyo yakanaka yekufungidzira kukosha kwakaderera zvakanyanya, kubva pakati pe10 ne60%.Saizvozvo, kana chibodzwa chakanaka kana mutemo ukashandiswa kutungamira kutanga kweantifungal therapy, varwere vazhinji vanogona kurapwa zvisina basa.Candida biomarkers inoratidza yakakwirira yakanaka yekufungidzira maitiro;zvisinei, havana kunzwisiswa uye nokudaro havakwanisi kuziva zviitiko zvose zve candidiasis invasive.The (1-3) -β-D-glucan (BG) assay, panfungal antigen test, inokurudzirwa sechishandiso chekuwedzera chekuongororwa kwemycoses invasive in high-risk hemato-oncological varwere.Basa rayo muhuwandu hwakawanda hweICU hunoramba huchitsanangurwa.Mamwe makiriniki ekusarudza nzira dzakasanganiswa neanoshanda maturusi emurabhoritari anodiwa kuitira kurapa varwere vakakodzera panguva yakakodzera nekuchengeta mitengo yekuongorora uye kurapwa yakaderera sezvinobvira.Nzira itsva yakarongwa naPosteraro uye vashandi pamwe navo munyaya yapfuura yeCritical Care inosangana nezvinodiwa izvi.Imwe chete yakanaka BG kukosha muvarwere vezvokurapa vanobvumirwa kuICU vane sepsis uye inotarisirwa kugara kwemazuva anopfuura 5 yakatangira zvinyorwa zvecandidemia ne1 kusvika kumazuva matatu nekunyatsoongorora kusati kwamboitika.Kushandisa iyi-point-point fungal screening pane yakasarudzwa subset yevarwere veICU vane inofungidzirwa 15 kusvika 20% yengozi yekuva necandidemia inzira inofadza uye inogona kudhura.Kana yakasimbiswa nekuferefeta kwakawanda, uye yakatambanudzirwa kune varwere vekuvhiya vari panjodzi huru yekuvhiyiwa candidiasis mushure mekuvhiyiwa kwemudumbu, iyi Bayesian-based risk stratification nzira ine chinangwa chekuwedzera hunyanzvi hwekiriniki nekuderedza kushandiswa kwezviwanikwa zvehutano zvinogona kurerutsa manejimendi evarwere vanorwara zvakanyanya vari panjodzi. ye invasive candidiasis.